Triptolide: Precision Inhibitor for Cancer and Immunology...

2025-10-21

Triptolide (PG490) empowers researchers with nanomolar-potency, mechanistic specificity as an IL-2/MMP-3/MMP7/MMP19 and NF-κB transcription inhibitor, enabling unparalleled control over genome activation, cancer invasion, and immune modulation. From dissecting early pluripotency in Xenopus embryos to inhibiting ovarian cancer metastasis and protecting cartilage in arthritis models, Triptolide’s versatility and reproducibility set it apart as an essential tool in advanced research workflows.